Dolonex dt: A Complete Guide to the Pain Reliever


Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to alleviate pain, inflammation, and fever. One such popular NSAID is Dolonex DT, which contains Piroxicam as its active ingredient. This article aims to provide a comprehensive guide to Dolonex DT, including its uses, dosage, side effects, interactions, and precautions.

What is Dolonex DT?

Dolonex DT is a brand name for the drug Piroxicam, which belongs to the class of NSAIDs. It is primarily used in the management of pain, inflammation, and stiffness associated with conditions like osteoarthritis, rheumatoid arthritis, gout, and other musculoskeletal disorders.

How Does Dolonex DT Work?

Piroxicam works by inhibiting the enzymes COX-1 and COX-2, which are responsible for the synthesis of prostaglandins. Prostaglandins are chemicals produced in response to injury or certain diseases and are responsible for causing pain, swelling, and inflammation. By blocking these enzymes, Piroxicam reduces the production of prostaglandins, thereby alleviating pain and inflammation.

Indications and Uses

Dolonex DT is indicated for the following conditions:

  1. Osteoarthritis: It is a degenerative joint disease that causes pain and stiffness in the joints.
  2. Rheumatoid Arthritis: An autoimmune condition that affects the joints, causing pain, swelling, and stiffness.
  3. Ankylosing Spondylitis: A type of arthritis that affects the spine and large joints.
  4. Gout: A form of arthritis characterized by sudden, severe attacks of pain, swelling, redness, and tenderness in the joints.

Dosage and Administration

  • The recommended dosage of Dolonex DT varies depending on the condition being treated.
  • It is usually taken once daily with or after food to reduce the risk of gastrointestinal side effects.
  • The tablet should be taken whole with a glass of water and should not be crushed or chewed.

Side Effects

While Dolonex DT is generally well-tolerated, it may cause some side effects in some individuals. Common side effects include:

  1. Gastrointestinal: Stomach pain, indigestion, nausea, vomiting, diarrhea, and ulcers.
  2. Cardiovascular: High blood pressure, fluid retention, and heart failure.
  3. Renal: Kidney problems such as reduced urine output and kidney failure.
  4. Hematological: Blood disorders like anemia and decreased platelet count.

Precautions and Warnings

  • Dolonex DT should be used with caution in individuals with a history of gastrointestinal ulcers, kidney disease, heart failure, or hypertension.
  • It should not be used in patients with a known hypersensitivity to Piroxicam or other NSAIDs.
  • Long-term use of Dolonex DT should be avoided as it may increase the risk of serious cardiovascular events.

Drug Interactions

Dolonex DT may interact with other medications, including:

  1. Anticoagulants: Increased risk of bleeding.
  2. Diuretics: Reduced diuretic effect.
  3. ACE Inhibitors: Reduced antihypertensive effect.
  4. Lithium: Increased lithium levels in the blood.


  1. Can Dolonex DT be taken on an empty stomach?
  2. It is recommended to take Dolonex DT with food to reduce the risk of gastrointestinal side effects.

  3. How long does it take for Dolonex DT to start working?

  4. Dolonex DT may start working within a few hours of taking the medication, but its full effects may take a few days to be felt.

  5. Can Dolonex DT be used for headache relief?

  6. Dolonex DT is not indicated for headache relief and should only be used for conditions it is prescribed for by a healthcare professional.

  7. Is Dolonex DT addictive?

  8. Dolonex DT is not known to be addictive when used as prescribed by a healthcare provider.

  9. Can Dolonex DT be taken during pregnancy?

  10. Dolonex DT should be avoided during pregnancy, especially in the third trimester, as it may cause harm to the fetus.


In conclusion, Dolonex DT is a commonly used NSAID for the management of pain and inflammation associated with various musculoskeletal disorders. It is important to use this medication under the guidance of a healthcare professional and to be aware of its potential side effects and interactions. If you experience any unusual symptoms while taking Dolonex DT, consult your doctor immediately.

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